ISO 21114:2026 specifies LC-UV determination of nicotine in pouches
The new international standard covers nicotine pouches and their fillings using HPLC or UPLC with ultraviolet detection.
ISO published ISO 21114:2026 for determination of nicotine in nicotine pouches and pouch fillings by liquid chromatography with ultraviolet detection. The free scope identifies HPLC or UPLC approaches.

Laboratories should check the purchased full text for preparation, calibration, performance and reporting requirements before claiming conformity. Publication of an international standard does not itself establish a Japanese legal requirement.